Date:
Wed, 22/05/201312:00-13:30
Location:
Danciger B building, Seminar room
"Examples of phenomena in cell physics : cell motility and cell division":
Cell phenomena are traditionally explained by molecular activation pathways. Signaling networks are indeed playing key roles in cell fate, for example in motility, division and death. However these switching events at the nanometer scale fail to provide satisfactory explanations for their microscopic read-outs which are at the micrometer scale. Our approach consists of trying to bridge this gap of three orders of magnitude in scales. We take the cell biology tools for performing experiments on individual cells and we develop and analyze the cell phenomena with condensed matter physics methods and frameworks.
I will present two examples illustrating this approach: i/ the cell ratchet, and ii/ the closure of a physiological ring made of molecular motors - the cytokinetic ring.
Cell phenomena are traditionally explained by molecular activation pathways. Signaling networks are indeed playing key roles in cell fate, for example in motility, division and death. However these switching events at the nanometer scale fail to provide satisfactory explanations for their microscopic read-outs which are at the micrometer scale. Our approach consists of trying to bridge this gap of three orders of magnitude in scales. We take the cell biology tools for performing experiments on individual cells and we develop and analyze the cell phenomena with condensed matter physics methods and frameworks.
I will present two examples illustrating this approach: i/ the cell ratchet, and ii/ the closure of a physiological ring made of molecular motors - the cytokinetic ring.