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Dr. Stas (Stanislav) Burov,James Franck Institute, University of Chicago | The Racah Institute of Physics

Dr. Stas (Stanislav) Burov,James Franck Institute, University of Chicago

Date: 
Wed, 18/12/201312:00-13:30
Location: 
Danciger B building, Seminar room
"Stochasticity of Intracellular Transport":
This talk will describe quantitative analyses of particle tracking data for systems with cytoskeletally associated motors to better understand the motions contributing to intracellular transport and, more generally, means for characterizing systems far from equilibrium. We exploit stochastic properties of single particle trajectories to establish "sanity" tests for experimentally collected data. Development of simple order parameters for 2d motion and studying its behavior for different models of transport in disordered media permits us to distinguish between random motion inside dense physical systems and molecular motors mediated transport. Furthermore, the stochastic properties of insulin-containg vesicles transport in beta cells provide a simple mechanism for how important beta cell functioning (biphasic insulin secretion) can arise.